Unusual case history, our experimental data shed some light on the Here we extend the list of drugs capable of cleaving the MLL gene,Īt least when cells are exposed in culture. The placental barrier and to induce such a chromosomal break at Several substances have been examined for their potential to cross Rearrangements of the MLL gene at chromosome 11q23. 1Ĭongenital and infant leukemia are often associated with Tobacco, marijuana, alcohol, and other toxins. Parental exposure to occupational and environmental toxins, use of There are many risk factors that may increase theĬhance of early induction of a leukaemic phenotype-for example, The opportunity to learn more about the underlying causes of in utero Rarity, congenital leukemia has stimulated much interest because of Keywords: congenital leukemia leukemia permethrin insecticide Ĭongenital leukemia is a rare disease which affects about one child in 200 000–250 000 live births a year. Incubation of the BV173 cell line with 50 µM ![]() Mother’s history, its potential to induce cleavage of the MLL gene inĬell culture was tested. Permethrin is considered comparatively safe, but, in view of the Because of arachnophobia, the mother had heavily abusedĪerosolized permethrin, a widely used household insecticide. Haematology and Oncology, Feulgenstr 12, 35392 Giessen, Germany ĪĬongenital leukemia with 11q23/MLL rearrangement in a preterm female This cookie, set by YouTube, registers a unique ID to store data on what videos from YouTube the user has seen.REPORT Congenital leukemia after heavy abuse of permethrinĬhildren’s University Hospital Giessen, Feulgenstr 12, 35392 YouTube sets this cookie to store the video preferences of the user using embedded YouTube video. YSC cookie is set by Youtube and is used to track the views of embedded videos on Youtube pages. This cookie is used for advertising, site analytics, and other operations.Ī cookie set by YouTube to measure bandwidth that determines whether the user gets the new or old player interface. The cookie helps in reporting and personalization as well.īing sets this cookie to recognize unique web browsers visiting Microsoft sites. The ANONCHK cookie, set by Bing, is used to store a user's session ID and also verify the clicks from ads on the Bing search engine. These cookies track visitors across websites and collect information to provide customized ads. YouTube sets this cookie via embedded youtube-videos and registers anonymous statistical data.Īdvertisement cookies are used to provide visitors with relevant ads and marketing campaigns. To determine the most generic cookie path that has to be used instead of the page hostname, Hotjar sets the _hjTLDTest cookie to store different URL substring alternatives until it fails. Hotjar sets this cookie to know whether a user is included in the data sampling defined by the site's daily session limit. Hotjar sets this cookie to know whether a user is included in the data sampling defined by the site's pageview limit. It stores a true/false value, indicating whether it was the first time Hotjar saw this user. Hotjar sets this cookie to identify a new user’s first session. This is a True/False flag set by the cookie. Hotjar sets this cookie to detect the first pageview session of a user. Some of the data that are collected include the number of visitors, their source, and the pages they visit anonymously. Installed by Google Analytics, _gid cookie stores information on how visitors use a website, while also creating an analytics report of the website's performance. This cookie is installed by Google Analytics. The cookie stores information anonymously and assigns a randomly generated number to recognize unique visitors. The _ga cookie, installed by Google Analytics, calculates visitor, session and campaign data and also keeps track of site usage for the site's analytics report. ![]() These cookies help provide information on metrics the number of visitors, bounce rate, traffic source, etc. Analytical cookies are used to understand how visitors interact with the website.
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